Cellular communication through extracellular vesicles and lipid droplets

Abstract Cellular communication is essential for effective coordination of biological processes. One major form intercellular occurs via the release extracellular vesicles (EVs). These mediate through transfer their cargo and are actively explored role in various diseases potential therapeutic diagnostic applications. Conversely, lipid droplets (LDs) that within cells. Lipid play roles evidence ability to between cells emerging. To date, there has been little interdisciplinary research looking at similarities interactions these two classes small vesicles. This review will compare commonalities differences EVs LDs including biogenesis secretion, isolation characterisation methodologies, composition, general heterogeneity discuss challenges opportunities both fields.